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Antacid Drugs Linked To Bone Fracture Risk

Nexium and Prilosec, powerful antacid drugs in the proton pump inhibitor family, may increase the risk of bone fractures, according to a new warning by the U.S. Food and Drug Administration.

Labeling on drugs in this class — both prescription and over-the-counter — will change to reflect this risk, the agency said.

The warning comes after several studies linked the drugs to increased fractures of the hip, wrist, spine, and also when taken for longer than one year in high doses. Another U.S. study suggests that the drugs may also increase risk of infection with C. difficile, a bacterium that can cause severe diarrhea.

Before making any changes, it is best to consult your medical doctor.

An estimated 113.4 million prescriptions for the drugs are written each year and large numbers are sold over the counter.

For more information, also read the FDA Drug Safety Communication.

Originally posted at InjuryBoard by Chrissie Cole